BDBM50157322 CHEMBL3786831

SMILES COc1cc2CC\C(=N/O)C(C)(C)c2cc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1

InChI Key InChIKey=DLZCCQFNABDGIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50157322   

TargetALK tyrosine kinase receptor(Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50157322(CHEMBL3786831)
Affinity DataIC50: 424nMAssay Description:Inhibition of wild type ALK (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Chungbuk National University

Curated by ChEMBL
LigandPNGBDBM50157322(CHEMBL3786831)
Affinity DataIC50: 600nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2017
Entry Details Article
PubMed