BDBM50157242 6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-2-phenethylamino-nicotinonitrile::CHEMBL359950

SMILES Cn1cncc1C(OCc1ccc(C#N)c(NCCc2ccccc2)n1)c1ccc(C#N)c(c1)-c1ccccc1C(F)(F)F

InChI Key InChIKey=OSUGBOGDUYJWRZ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50157242   

LigandPNGBDBM50157242(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of Bovine farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157242(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Bovine geranylgeranyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50157242(6-[(6-Cyano-2''-trifluoromethyl-biphenyl-3-yl)-(3-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration against H-ras processing in transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed