BDBM50157145 (2S,3R)-3-(4-Hydroxy-phenyl)-2-{4-[2-((R)-3-methyl-pyrrolidin-1-yl)-ethoxy]-phenyl}-2,3-dihydro-benzo[1,4]oxathiin-6-ol::(2S,3R)-3-(4-hydroxyphenyl)-2-(4-(2-((R)-3-methylpyrrolidin-1-yl)ethoxy)phenyl)-2,3-dihydrobenzo[b][1,4]oxathiin-6-ol::CHEMBL183584

SMILES C[C@@H]1CCN(CCOc2ccc(cc2)[C@@H]2Oc3ccc(O)cc3S[C@@H]2c2ccc(O)cc2)C1

InChI Key InChIKey=CTKCIBJHOHRDAM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50157145   

TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157145((2S,3R)-3-(4-Hydroxy-phenyl)-2-{4-[2-((R)-3-methyl...)
Affinity DataIC50: 161nMAssay Description:Inhibition of binding to recombinant human estrogen receptor betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157145((2S,3R)-3-(4-Hydroxy-phenyl)-2-{4-[2-((R)-3-methyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of bindign to recombinant human estrogen receptor alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157145((2S,3R)-3-(4-Hydroxy-phenyl)-2-{4-[2-((R)-3-methyl...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human estrogen receptor 2 using tritiated estradiol incubated for 3 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157145((2S,3R)-3-(4-Hydroxy-phenyl)-2-{4-[2-((R)-3-methyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of binding to recombinant human ERalpha by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157145((2S,3R)-3-(4-Hydroxy-phenyl)-2-{4-[2-((R)-3-methyl...)
Affinity DataIC50: 161nMAssay Description:Inhibition of binding to recombinant human ERbeta by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157145((2S,3R)-3-(4-Hydroxy-phenyl)-2-{4-[2-((R)-3-methyl...)
Affinity DataIC50: 3nMAssay Description:Inhibition of ERalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed