BDBM50156759 5-((2-(3,5-dichloro-2-hydroxybenzylideneamino)phenylthio)methyl)-4-(hydroxymethyl)-2-methylpyridin-3-ol::5-(2-{[1-(3,5-dichloro-2-hydroxyphenyl)meth-(E)-ylidene]amino}phenylsulfanylmethyl-4-hydroxymethyl-2-methylpyridin-3-ol::CHEMBL220458

SMILES Cc1ncc(CSc2ccccc2\N=C\c2cc(Cl)cc(Cl)c2O)c(CO)c1O

InChI Key InChIKey=ZLSLKKKKVPNPDP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156759   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156759(5-(2-{[1-(3,5-dichloro-2-hydroxyphenyl)meth-(E)-yl...)
Affinity DataIC50: 7.43E+4nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156759(5-(2-{[1-(3,5-dichloro-2-hydroxyphenyl)meth-(E)-yl...)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of Sirt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50156759(5-(2-{[1-(3,5-dichloro-2-hydroxyphenyl)meth-(E)-yl...)
Affinity DataIC50: 7.43E+4nMAssay Description:Inhibition of SIRT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMed