BDBM50156507 (1R,6S,7R)-4-(4-Nitro-phenyl)-3,5-dioxo-2,4,8-triaza-tricyclo[5.2.1.0*2,6*]decane-8-carboxylic acid tert-butyl ester::CHEMBL364393

SMILES CC(C)(C)OC(=O)N1C[C@H]2C[C@@H]1c1c(O)n(-c3ccc(cc3)[N+]([O-])=O)c(=O)n21

InChI Key InChIKey=CQJUOFHJOFTOGP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156507   

TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156507((1R,6S,7R)-4-(4-Nitro-phenyl)-3,5-dioxo-2,4,8-tria...)
Affinity DataIC50: 250nMAssay Description:In vitro antagonistic activity against androgen receptor of MDA-453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156507((1R,6S,7R)-4-(4-Nitro-phenyl)-3,5-dioxo-2,4,8-tria...)
Affinity DataIC50: 2.39E+3nMAssay Description:In vitro antagonistic activity against mutant androgen receptor of LNCap cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50156507((1R,6S,7R)-4-(4-Nitro-phenyl)-3,5-dioxo-2,4,8-tria...)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]DHT from androgen receptor of human MDA-453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed