BDBM50156133 CHEMBL3782009

SMILES CC(=O)Nc1nccn1CCOc1ccc(NC(=O)Nc2cc(nn2-c2ccc(C)cc2)C(C)(C)C)c2ccccc12

InChI Key InChIKey=PPJBCBIGKHEBIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156133   

TargetMitogen-activated protein kinase 12(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156133(CHEMBL3782009)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant p38 gamma assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156133(CHEMBL3782009)
Affinity DataIC50: 3.22E+3nMAssay Description:Inhibition of HCK (unknown origin) preincubated for 2 hrs followed by FRET peptide addition measured after 1 hr by Z-LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Sygnature Discovery

Curated by ChEMBL
LigandPNGBDBM50156133(CHEMBL3782009)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant p38 alpha assessed as phosphorylation of MAPKAP-K2 preincubated for 2 hrs followed by FRET peptide and MAPKAP-K2 addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed