BDBM50156123 CHEMBL3780219

SMILES CNc1nc(Nc2ccc(C)c(N)c2)ncc1C(=O)Nc1cc(NC(=O)c2cccc(c2)C(F)(F)F)ccc1C

InChI Key InChIKey=GXMFPDCIAWSZFR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50156123   

TargetTyrosine-protein kinase ABL1(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 70nMAssay Description:Inhibition of full length recombinant human ABL1 expressed in Baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetEpithelial discoidin domain-containing receptor 1(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 292nMAssay Description:Inhibition of GST-tagged human DDR1 (440 to 876 residues) expressed in Baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetDiscoidin domain-containing receptor 2(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 457nMAssay Description:Inhibition of recombinant human GST-tagged DDR2 expressed in Baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of His-tagged recombinant human c-Kit without catalytic domain expressed in mammalian expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 62nMAssay Description:Inhibition of full length recombinant GST-tagged human p38-alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
High Magnetic Field Laboratory

Curated by ChEMBL
LigandPNGBDBM50156123(CHEMBL3780219)
Affinity DataIC50: 90nMAssay Description:Inhibition of full length recombinant human C-terminal His-tagged SRC expressed in Baculovirus expression systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/12/2017
Entry Details Article
PubMed