BDBM50156061 CHEMBL365797::CHEMBL556609::N-(4-chloro-2-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)picolinamide::Pyridine-2-carboxylic acid [4-chloro-2-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-phenyl]-amide

SMILES Clc1ccc(NC(=O)c2ccccn2)c(CN2C(=O)c3ccccc3C2=O)c1

InChI Key InChIKey=USYDGTLOPLIFMI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50156061   

TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50156061(Pyridine-2-carboxylic acid [4-chloro-2-(1,3-dioxo-...)
Affinity DataEC50:  250nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50156061(Pyridine-2-carboxylic acid [4-chloro-2-(1,3-dioxo-...)
Affinity DataEC50:  245nMAssay Description:Effective concentration against metabotropic glutamate receptor 5 of human transfected into CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50156061(Pyridine-2-carboxylic acid [4-chloro-2-(1,3-dioxo-...)
Affinity DataEC50:  250nMAssay Description:Activity at human mGluR5 expressed in CHO cells assessed as potentiation of glutamate response by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2012
Entry Details Article
PubMed