BDBM50155807 3-(1-Methyl-1,2,3,4-tetrahydro-quinolin-3-yl)-4-[1-(3-5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl-propionyl)-piperidin-4-yl]-butyric acid::CHEMBL362114

SMILES CN1CC(Cc2ccccc12)C(CC1CCN(CC1)C(=O)CCc1ccc2CCCNc2n1)CC(O)=O

InChI Key InChIKey=JJAXPFWZGVIPSO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155807   

TargetIntegrin alpha-V/beta-3(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50155807(3-(1-Methyl-1,2,3,4-tetrahydro-quinolin-3-yl)-4-[1...)
Affinity DataIC50: 49nMAssay Description:Inhibitory concentration for human vitronectin binding to immobilized alphaV-beta3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50155807(3-(1-Methyl-1,2,3,4-tetrahydro-quinolin-3-yl)-4-[1...)
Affinity DataIC50: 180nMAssay Description:Inhibitory concentration for human vitronectin binding to immobilized alphaV-beta5 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50155807(3-(1-Methyl-1,2,3,4-tetrahydro-quinolin-3-yl)-4-[1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory concentration for biotinylated fibrinogen binding to immobilized alpha IIb beta-3 integrinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed