BDBM50155774 CHEMBL3780776

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N1CCN(CC1)[C@@H]1CCN(C[C@@H]1c1ccccc1)C(=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=WCJDWNUHDMSTQS-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50155774   

TargetMu-type opioid receptor(Guinea pig)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155774(CHEMBL3780776)
Affinity DataIC50: 137nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155774(CHEMBL3780776)
Affinity DataIC50: 384nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155774(CHEMBL3780776)
Affinity DataKi:  0.990nMAssay Description:Displacement of [3H]SP from human NK1 receptor transfected in CHO cells by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155774(CHEMBL3780776)
Affinity DataKi:  9.90nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in rat brain membrane after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50155774(CHEMBL3780776)
Affinity DataKi:  533nMAssay Description:Displacement of [3H]DSLET from delta opioid receptor in rat brain membrane after 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed