BDBM50155770 CHEMBL3781885

SMILES N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccc(NC(=O)OCc3ccccc3)c(c2)N2CCOCC2)cc1

InChI Key InChIKey=NXKYPBDDPFDALC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50155770   

TargetREST corepressor 1 [4-485](Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155770(CHEMBL3781885)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant KDM1A/CoREST expressed in Escherichia coli using mono-methylated H3-K4 peptide as substrate assessed as H2O2 release ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155770(CHEMBL3781885)
Affinity DataIC50: 2.78E+4nMAssay Description:Inhibition of human recombinant MAOB expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetLysine-specific histone demethylase 2(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155770(CHEMBL3781885)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of KDM1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
European Institute of Oncology

Curated by ChEMBL
LigandPNGBDBM50155770(CHEMBL3781885)
Affinity DataIC50: 345nMAssay Description:Inhibition of human recombinant MAOA expressed in Pichia pastoris preincubated for 15 mins measured after 30 mins by bioluminescent-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2017
Entry Details Article
PubMed