BDBM50155713 1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-ylsulfanyl)-butoxy]-phenyl}-3-methyl-butan-1-one::CHEMBL182166::US10099993, Compound 184

SMILES CC(C)CC(=O)c1ccc(OCCCCSc2ccccn2)c(C)c1O

InChI Key InChIKey=XFBJZQIVKIQSON-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155713   

TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155713(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-ylsulfanyl)-...)
Affinity DataEC50:  1.53E+3nMAssay Description:Binding affinity towards human metabotropic glutamate receptor 2 determined by [35S]GTP gamma S binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155713(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-ylsulfanyl)-...)
Affinity DataEC50: >1.00E+4nMpH: 7.3 T: 2°CAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 3(Human)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM50155713(1-{2-Hydroxy-3-methyl-4-[4-(pyridin-2-ylsulfanyl)-...)
Affinity DataEC50: >3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2019
Entry Details
Go to US Patent