BDBM50155676 CHEMBL3781161

SMILES COc1c(F)cccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1

InChI Key InChIKey=YSENRWGJQXAGSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155676   

LigandPNGBDBM50155676(CHEMBL3781161)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50155676(CHEMBL3781161)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50155676(CHEMBL3781161)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed