BDBM50155653 CHEMBL1080791::CHEMBL185975::N-[9-Oxo-6-(3-pyrrolidin-1-yl-propionylamino)-9,10-dihydro-acridin-3-yl]-3-pyrrolidin-1-yl-propionamide

SMILES Oc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12

InChI Key InChIKey=SWVBRNFIKZGFGD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155653   

TargetTelomerase reverse transcriptase(Human)
University of London

Curated by ChEMBL
LigandPNGBDBM50155653(CHEMBL1080791 | CHEMBL185975 | N-[9-Oxo-6-(3-pyrro...)
Affinity DataEC50:  8.10E+3nMAssay Description:Concentration required to inhibit 50% of telomerase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of London

Curated by ChEMBL
LigandPNGBDBM50155653(CHEMBL1080791 | CHEMBL185975 | N-[9-Oxo-6-(3-pyrro...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of telomerase in human A2780 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed