BDBM50155476 2-[1-(4-Dimethylamino-phenyl)-meth-(E)-ylidene]-6-hydroxy-3,4-dihydro-2H-naphthalen-1-one::2-{1-[4-(dimethylamino)phenyl]methylidene}-6-hydroxy-3,4-dihydro-2H-naphthalen-1-one::CHEMBL365686

SMILES CN(C)c1ccc(\C=C2/CCc3cc(O)ccc3C2=O)cc1

InChI Key InChIKey=VDXYEGLOBGVAHQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155476   

LigandPNGBDBM50155476(2-{1-[4-(dimethylamino)phenyl]methylidene}-6-hydro...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against 25-hydroxyvitamin D3 24-hydroxylase of rat kidney mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Pecs

Curated by ChEMBL
LigandPNGBDBM50155476(2-{1-[4-(dimethylamino)phenyl]methylidene}-6-hydro...)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of human recombinant MIF ketonase activity using phenylpyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMacrophage migration inhibitory factor(Human)
University of Pecs

Curated by ChEMBL
LigandPNGBDBM50155476(2-{1-[4-(dimethylamino)phenyl]methylidene}-6-hydro...)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of human recombinant MIF enolase activity using phenylpyruvate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed