BDBM50155469 2-(4-Hydroxy-benzyl)-6-methoxy-3,4-dihydro-2H-naphthalen-1-one::2-(4-hydroxybenzyl)-6-methoxy-3,4-dihydro-2H-naphthalen-1-one::CHEMBL185684

SMILES COc1ccc2C(=O)C(Cc3ccc(O)cc3)CCc2c1

InChI Key InChIKey=QXKFHJXUOCOYOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155469   

LigandPNGBDBM50155469(2-(4-hydroxybenzyl)-6-methoxy-3,4-dihydro-2H-napht...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory activity against 25-hydroxyvitamin D3 24-hydroxylase of rat kidney mitochondriaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
Northwest University

Curated by ChEMBL
LigandPNGBDBM50155469(2-(4-hydroxybenzyl)-6-methoxy-3,4-dihydro-2H-napht...)
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of 25-hydroxy-[26,27-methyl-3H]-vitamin D3 from CYP24 in 1,25(OH)2D3-treated human DU-145 cells using 25-(OH)D3 as substrate pretreated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed