BDBM50155447 1,3,6,7-Tetrahydroxy-xanthen-9-one::1,3,6,7-tetrahydroxyxantone::CHEMBL187265

SMILES c1c(cc2c(c1O)C(=O)c3cc(c(cc3O2)O)O)O

InChI Key InChIKey=ZHTQCPCDXKMMLU-UHFFFAOYSA-N

Data  1 KI  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50155447   

TargetFatty acid synthase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-tetrahydroxyxantone | 1,3,6,7-Tetrahydroxy...)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of FASMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Unne

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-tetrahydroxyxantone | 1,3,6,7-Tetrahydroxy...)
Affinity DataIC50: 2.50E+4nMAssay Description:Concentration required to inhibit monoamine oxidase activity by 50%More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-tetrahydroxyxantone | 1,3,6,7-Tetrahydroxy...)
Affinity DataIC50: 5.31E+5nMAssay Description:Inhibition of ACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-tetrahydroxyxantone | 1,3,6,7-Tetrahydroxy...)
Affinity DataIC50: 2.17E+4nMAssay Description:Inhibition of bovine Xanthine oxidase assessed as reduction in uric acid level by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-tetrahydroxyxantone | 1,3,6,7-Tetrahydroxy...)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of human recombinant MMP1 catalytic domain incubated for 20 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Human)
University of Toyama

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-tetrahydroxyxantone | 1,3,6,7-Tetrahydroxy...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant C-terminal 6xHis-tagged MTH1 (3 to 156 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-tetrahydroxyxantone | 1,3,6,7-Tetrahydroxy...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetAngiotensin-converting enzyme(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50155447(1,3,6,7-tetrahydroxyxantone | 1,3,6,7-Tetrahydroxy...)
Affinity DataKi:  2.50E+5nMAssay Description:Inhibition of ACE by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed