BDBM50155357 7-Chloro-4-[2-((R)-1-methyl-6-trifluoromethyl-piperidin-2-yl)-ethoxy]-2-oxo-3-((S)-3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid pyrimidin-4-ylamide::CHEMBL365366

SMILES CN1[C@H](CCOc2c(-c3cc(C)c(C)c(C)c3)c(=O)[nH]c3cc(Cl)c(cc23)C(=O)Nc2ccncn2)CCC[C@@H]1C(F)(F)F

InChI Key InChIKey=ZUTIZSMLCDYNNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155357   

TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155357(7-Chloro-4-[2-((R)-1-methyl-6-trifluoromethyl-pipe...)
Affinity DataIC50: 2nMAssay Description:Binding affinity towards human gonadotropin releasing hormone receptor expressed in CHO cells was determined by using [125I]-buserelin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50155357(7-Chloro-4-[2-((R)-1-methyl-6-trifluoromethyl-pipe...)
Affinity DataIC50: 18nMAssay Description:Inhibition of GnRH-stimulated phosphatidyl inositol hydrolysis in CHO cells expressing GnRH receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed