BDBM50155301 CHEMBL3781659

SMILES OC(=O)CSc1nnc(NC(=S)Nc2cccc(c2)C(F)(F)F)s1

InChI Key InChIKey=LUNMJIBTIDLVBX-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155301   

TargetPolyphenol oxidase 2(White button mushroom)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50155301(CHEMBL3781659)
Affinity DataIC50: 6.13E+3nMAssay Description:Inhibition of diphenolase activity of mushroom tyrosinase preincubated for 10 mins followed by addition of L-DOPA measured for 5 mins by spectrophoto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50155301(CHEMBL3781659)
Affinity DataIC50: 15nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as a substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetPolyphenol oxidase 2(White button mushroom)
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50155301(CHEMBL3781659)
Affinity DataKi:  8.13E+3nMAssay Description:Noncompetitive inhibition of diphenolase activity of mushroom tyrosinase preincubated for 10 mins followed by addition of L-DOPA measured for 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed