BDBM50155225 CHEMBL365855::N-(5-Cyclobutyl-thiazol-2-yl)-2-phenyl-acetamide::N-(5-cyclobutylthiazol-2-yl)-2-phenylacetamide

SMILES O=C(Cc1ccccc1)Nc1ncc(s1)C1CCC1

InChI Key InChIKey=YIAFFFACXVWBIZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155225   

TargetCyclin-dependent kinase 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155225(N-(5-cyclobutylthiazol-2-yl)-2-phenylacetamide | N...)
Affinity DataIC50: 25nMAssay Description:Concentration required for inhibition of cyclin-dependent kinase 5 was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50155225(N-(5-cyclobutylthiazol-2-yl)-2-phenylacetamide | N...)
Affinity DataIC50: 74nMAssay Description:Concentration required for inhibition of cyclin dependant kinase 2-cyclin E was measured by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50155225(N-(5-cyclobutylthiazol-2-yl)-2-phenylacetamide | N...)
Affinity DataIC50: 64nMAssay Description:Inhibition of CDK5/p25 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed