BDBM50155149 4-(3-Methyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl-2,4-dihydro-pyrazol-3-one::CHEMBL366079

SMILES Cc1c(\C=C2/C(=O)NN=C2c2cnccn2)[nH]c2ccccc12

InChI Key InChIKey=BVXORFMGHHUQAM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50155149   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155149(4-(3-Methyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50: 60nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) without DTT (dithiothreitol)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Bioresearch Center

Curated by ChEMBL
LigandPNGBDBM50155149(4-(3-Methyl-1H-indol-2-ylmethylene)-5-pyrazin-2-yl...)
Affinity DataIC50: 140nMAssay Description:Inhibition of Vascular endothelial growth factor receptor 2(KDR) with DTT (dithiothreitol)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed