BDBM50155128 CHEMBL183203::N,N-dimethyl-2-(3-(phenylsulfonyl)-1H-indol-1-yl)ethanamine::[2-(3-Benzenesulfonyl-indol-1-yl)-ethyl]-dimethyl-amine

SMILES CN(C)CCn1cc(c2ccccc12)S(=O)(=O)c1ccccc1

InChI Key InChIKey=JRCURRGCAIWUMY-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50155128   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50155128(N,N-dimethyl-2-(3-(phenylsulfonyl)-1H-indol-1-yl)e...)
Affinity DataEC50:  366nMAssay Description:Agonist activity at human cloned 5HT6 receptor expressed in HeLa cells assessed as induction of adenylyl cyclase activity by RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50155128(N,N-dimethyl-2-(3-(phenylsulfonyl)-1H-indol-1-yl)e...)
Affinity DataKi:  20nMAssay Description:Binding affinity against human 5-hydroxytryptamine 6 receptor transfected in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50155128(N,N-dimethyl-2-(3-(phenylsulfonyl)-1H-indol-1-yl)e...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed