BDBM50154998 2-[2-(5-Fluoro-4''-methyl-biphenyl-3-yl)-2H-tetrazol-5-yl]-pyridine::CHEMBL184337

SMILES Cc1ccc(cc1)-c1cc(F)cc(c1)-n1nnc(n1)-c1ccccn1

InChI Key InChIKey=YWQAVBIVXGNXCA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154998   

TargetMetabotropic glutamate receptor 5(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50154998(2-[2-(5-Fluoro-4''-methyl-biphenyl-3-yl)-2H-tetraz...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assay using glutamate (10 uM) as agonistMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50154998(2-[2-(5-Fluoro-4''-methyl-biphenyl-3-yl)-2H-tetraz...)
Affinity DataIC50: 1.47E+3nMAssay Description:In vitro antagonistic activity against Metabotropic glutamate receptor 5 in [Ca2+] flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed