BDBM50154813 CHEMBL3774451

SMILES Fc1ccc(cc1)-n1nnc(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c1C(F)(F)F

InChI Key InChIKey=ULHLSSWDQFLSBL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50154813   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50: 86nMAssay Description:Inhibition of KDR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50: 325nMAssay Description:Inhibition of cKit (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50: 582nMAssay Description:Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Jiangxi Science and Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50154813(CHEMBL3774451)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of cMet (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed