BDBM50154616 2-Fluoro-4b,9,10-triaza-benzo[b]fluorene-5,11-dione::4-aza-8-fluorotryptanthrin::CHEMBL187652::US10669273, Compound CY-1-2

SMILES Fc1ccc-2c(c1)C(=O)c1nc3ncccc3c(=O)n-21

InChI Key InChIKey=AKHMUNBSKUODAD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154616   

TargetMO15-related protein kinase Pfmrk(malaria parasite P. falciparum)
Walter Reed Army Institute of Research

Curated by ChEMBL
LigandPNGBDBM50154616(4-aza-8-fluorotryptanthrin | 2-Fluoro-4b,9,10-tria...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Plasmodium falciparum cyclin-dependent kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM50154616(4-aza-8-fluorotryptanthrin | 2-Fluoro-4b,9,10-tria...)
Affinity DataIC50: 5.5nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent

TargetIndoleamine 2,3-dioxygenase 1(Human)
Peking University

US Patent
LigandPNGBDBM50154616(4-aza-8-fluorotryptanthrin | 2-Fluoro-4b,9,10-tria...)
Affinity DataIC50: 5.5nMAssay Description:Experimental method: IDO-1 can oxidatively cleave the indole ring of tryptophan to form N-formylkynurenine. Referring to the method in the literature...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent