BDBM50154580 1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethylamine::CHEMBL417784

SMILES Cc1cc(C)cc(COCC(N)C(c2ccccc2)c2ccccc2)c1

InChI Key InChIKey=WWBFKWXDEJRSHS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154580   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50154580(1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethy...)
Affinity DataIC50: 9.30nMAssay Description:Binding affinity towards human Tachykinin receptor 1 expressed in CHO cells by the displacement of [125 I] substance PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50154580(1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethy...)
Affinity DataIC50: 9.30nMAssay Description:Binding affinity of compound was determined from inhibition of [125I]- substance P binding to the hNK1 receptor in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50154580(1-(3,5-Dimethyl-benzyloxymethyl)-2,2-diphenyl-ethy...)
Affinity DataIC50: 9.30nMAssay Description:Inhibition of substance P binding to Tachykinin receptor 1 in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed