BDBM50154572 1-Amino-2-[1-(3,5-bis-trifluoromethyl-benzyloxymethyl)-2,2-diphenyl-ethylamino]-ethanol::2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2-diphenyl-ethylamino]-acetamide::CHEMBL28055

SMILES NC(=O)CNC(COCc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(c1ccccc1)c1ccccc1

InChI Key InChIKey=MWKJCJFYJWIFLL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50154572   

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50154572(2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2...)
Affinity DataIC50: 0.850nMAssay Description:Binding affinity towards Neurokinin -1(NK-1) receptor of human by using [125I]- Tyr8 substance P as a radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50154572(2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2...)
Affinity DataIC50: 0.850nMAssay Description:Binding affinity towards human Tachykinin receptor 1 expressed in CHO cells by the displacement of [125 I] substance PMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article

TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50154572(2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2...)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of substance P binding to Tachykinin receptor 1 in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSubstance-P receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50154572(2-[1-(3,5-Bis-trifluoromethyl-benzyloxymethyl)-2,2...)
Affinity DataIC50: 0.530nMAssay Description:Inhibition of substance P binding to Tachykinin receptor 1 in Chinese hamster ovary cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed