BDBM50154401 CHEMBL3774612

SMILES CS(=O)(=O)c1ccc(cc1)-c1cc(nc(NCc2ccc(I)cc2)n1)C(F)(F)F

InChI Key InChIKey=ORUXSSHNISKZNE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154401   

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50154401(CHEMBL3774612)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ovine COX-1 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluorescence analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50154401(CHEMBL3774612)
Affinity DataIC50: 850nMAssay Description:Inhibition of recombinant human COX-2 preincubated for 5 mins followed by addition of arachidonic acid as substrate measured after 2 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed