BDBM50154362 CHEMBL3775798

SMILES [H][C@]12C[C@H](CN1CCOC2)n1c2ccc(\C=C3/c4ccccc4COc4cc(F)ccc34)cc2[nH]c1=O

InChI Key InChIKey=CZHIJMGMBQCQDA-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50154362   

TargetProgesterone receptor(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154362(CHEMBL3775798)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GST-tagged human progesterone receptor LBD domain expressed in insect cells by Gal4-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154362(CHEMBL3775798)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of GST-tagged human glucocorticoid receptor LBD domain expressed in insect cells at by Gal4-based fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154362(CHEMBL3775798)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of estrogen receptor (unknown origin) by Gal4-based luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154362(CHEMBL3775798)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154362(CHEMBL3775798)
Affinity DataIC50: 5.81E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vitae Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50154362(CHEMBL3775798)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Instituto De Qu£Mica M£Dica (Iqm-Csic)

Curated by ChEMBL
LigandPNGBDBM50154362(CHEMBL3775798)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]-cortisol from MR overexpressed in human 293 cells measured after 2 hrs by Microbeta scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed