BDBM50154348 CHEMBL3774704

SMILES O=C1OCC\C1=C/c1ccc2ncsc2c1

InChI Key InChIKey=FMOOGIYSVBVFIT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50154348   

TargetEpidermal growth factor receptor(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50154348(CHEMBL3774704)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 15 mins in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
LigandPNGBDBM50154348(CHEMBL3774704)
Affinity DataIC50: 60nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged DYRK2 expressed in Escherichia coli BL21(DE3) cells using KKISGRLSPIMTEQ-NH2 as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
LigandPNGBDBM50154348(CHEMBL3774704)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of full length recombinant human GST-tagged DYRK1B expressed in insect cells using KKISGRLSPIMTEQ-NH2 as substrate incubated for 15 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
LigandPNGBDBM50154348(CHEMBL3774704)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged DYRK1A catalytic domain expressed in Escherichia coli BL21(DE3) cells using KKISGRLSPIMTEQ-NH2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50154348(CHEMBL3774704)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human GST-tagged CLK1 catalytic domain (129 to 484 residues) expressed in Escherichia coli using GRSRSRSRSRSRSRSR as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
LigandPNGBDBM50154348(CHEMBL3774704)
Affinity DataIC50: 200nMAssay Description:Inhibition of tetracycline-inducible EGFP-DYRK1A (unknown origin) expressed in HEK293 cells coexpressing full length human EGFP-tau protein assessed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed