BDBM50154254 CHEMBL3775705

SMILES COC(=O)[C@H](Cc1ccccc1)NC(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=QJMOTTQOIGBRCP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154254   

TargetKallikrein-5 [D153N](Human)
Universidade Federal Fluminense

Curated by ChEMBL
LigandPNGBDBM50154254(CHEMBL3775705)
Affinity DataIC50: 112nMAssay Description:Inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetKallikrein-5 [D153N](Human)
Universidade Federal Fluminense

Curated by ChEMBL
LigandPNGBDBM50154254(CHEMBL3775705)
Affinity DataKi:  120nMAssay Description:Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed