BDBM50154252 CHEMBL3774934

SMILES COC(=O)[C@@H]1CCCN1C(=O)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OC(C)(C)C

InChI Key InChIKey=LFYGDEBHJLKLSP-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50154252   

TargetKallikrein-5 [D153N](Human)
Universidade Federal Fluminense

Curated by ChEMBL
LigandPNGBDBM50154252(CHEMBL3774934)
Affinity DataIC50: 122nMAssay Description:Inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by spectrofluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed
TargetKallikrein-5 [D153N](Human)
Universidade Federal Fluminense

Curated by ChEMBL
LigandPNGBDBM50154252(CHEMBL3774934)
Affinity DataKi:  130nMAssay Description:Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2017
Entry Details Article
PubMed