BDBM50154236 CHEMBL187142::[6-Benzhydryl-1-(4-fluoro-benzyl)-piperidin-3-yl]-(4-fluoro-benzyl)-amine

SMILES Fc1ccc(CNC2CCC(C(c3ccccc3)c3ccccc3)N(Cc3ccc(F)cc3)C2)cc1

InChI Key InChIKey=KVWQMPXTOQRZSX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154236   

TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154236([6-Benzhydryl-1-(4-fluoro-benzyl)-piperidin-3-yl]-...)
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154236([6-Benzhydryl-1-(4-fluoro-benzyl)-piperidin-3-yl]-...)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154236([6-Benzhydryl-1-(4-fluoro-benzyl)-piperidin-3-yl]-...)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed