BDBM50154231 8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicyclo[3.3.1]nonane::CHEMBL280518

SMILES COc1ccc(cc1)N1CCN2CC1CCC2C(c1ccccc1)c1ccccc1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154231   

TargetSodium-dependent dopamine transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154231(8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...)
Affinity DataIC50: 68.9nMAssay Description:Inhibition of [3H]WIN-35428 binding to dopamine transporter of rat striatumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154231(8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...)
Affinity DataIC50: 5.83E+3nMAssay Description:Inhibition of [3H]citalopram binding to serotonin transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50154231(8-Benzhydryl-4-(4-methoxy-phenyl)-1,4-diaza-bicycl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]nisoxetine binding to norepinephrine transporter of rat cerebral cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed