BDBM50154200 7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydronaphthalen-2-ol::CHEMBL187635

SMILES CO[C@H]1Cc2ccc(O)cc2C(C)(C)[C@@H]1N

InChI Key InChIKey=IGSNSHHFXGJMKP-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50154200   

TargetMu-type opioid receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50154200(7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydron...)
Affinity DataEC50:  234nMAssay Description:Agonist activity at human cloned mu opioid receptor expressed in CHO cells assessed as stimulation of [35S]-GTP[gammaS] bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50154200(7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydron...)
Affinity DataKi:  18nMAssay Description:Inhibition of [3H]DAMGO binding to human Mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50154200(7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydron...)
Affinity DataKi:  149nMAssay Description:Inhibition of [3H]U-69593 binding to human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50154200(7-amino-6-methoxy-8,8-dimethyl-5,6,7,8-tetrahydron...)
Affinity DataKi:  2.43E+3nMAssay Description:Inhibition of [3H]C1-DPDPE binding to human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2012
Entry Details Article
PubMed