BDBM50154084 7-Bromo-2-(3-fluoro-4-hydroxy-phenyl)-benzooxazol-5-ol::7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol-5-ol::CHEMBL187207

SMILES Oc1cc(Br)c2oc(nc2c1)-c1ccc(O)c(F)c1

InChI Key InChIKey=GGHZQYDERZQJFP-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50154084   

TargetEstrogen receptor beta(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol...)
Affinity DataIC50: 199nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to mouse ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol...)
Affinity DataIC50: 260nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER beta expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol...)
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol...)
Affinity DataIC50: 171nMAssay Description:Inhibition of [3H]17-beta-estradiol binding to rat ER alpha expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154084(7-bromo-2-(3-fluoro-4-hydroxyphenyl)benzo[d]oxazol...)
Affinity DataIC50: 3nMAssay Description:Binding affinity to ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed