BDBM50154064 2-(2-Fluoro-4-hydroxy-phenyl)-5-hydroxy-benzooxazole-7-carbonitrile::2-(2-fluoro-4-hydroxyphenyl)-5-hydroxybenzo[d]oxazole-7-carbonitrile::CHEMBL189658

SMILES Oc1ccc(-c2nc3cc(O)cc(C#N)c3o2)c(F)c1

InChI Key InChIKey=DEFIOUDVRMACDV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50154064   

TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154064(2-(2-fluoro-4-hydroxyphenyl)-5-hydroxybenzo[d]oxaz...)
Affinity DataIC50: 2.40nMAssay Description:Inhibitory concentration against human ER beta expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154064(2-(2-fluoro-4-hydroxyphenyl)-5-hydroxybenzo[d]oxaz...)
Affinity DataIC50: 138nMAssay Description:Inhibitory concentration against human ER alpha expressed in Escherichia coli was determined using [3H]17-beta-estradiol as radio ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEstrogen receptor beta(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50154064(2-(2-fluoro-4-hydroxyphenyl)-5-hydroxybenzo[d]oxaz...)
Affinity DataIC50: 2.40nMAssay Description:Binding affinity to ERbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed