BDBM50153869 CHEMBL365830::N-[3-(6,7-Dimethoxy-quinazolin-4-ylamino)-phenyl]-3-dimethylamino-benzamide

SMILES COc1cc2ncnc(Nc3cccc(NC(=O)c4cccc(c4)N(C)C)c3)c2cc1OC

InChI Key InChIKey=GGJVKAJEYVJTHX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153869   

TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153869(N-[3-(6,7-Dimethoxy-quinazolin-4-ylamino)-phenyl]-...)
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against alpha mitogen activated protein kinase p38 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153869(N-[3-(6,7-Dimethoxy-quinazolin-4-ylamino)-phenyl]-...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibitory concentration against Epidermal growth factor receptor tyrosine kinase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed