BDBM50153866 CHEMBL182397::N-[3-(6,7-Dimethoxy-quinazolin-4-ylamino)-2-fluoro-phenyl]-benzamide

SMILES COc1cc2ncnc(Nc3cccc(NC(=O)c4ccccc4)c3F)c2cc1OC

InChI Key InChIKey=OQUOTBSSEUPKNG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153866   

TargetEpidermal growth factor receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153866(N-[3-(6,7-Dimethoxy-quinazolin-4-ylamino)-2-fluoro...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against Epidermal growth factor receptor tyrosine kinase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153866(N-[3-(6,7-Dimethoxy-quinazolin-4-ylamino)-2-fluoro...)
Affinity DataIC50: 690nMAssay Description:Inhibitory concentration against alpha mitogen activated protein kinase p38 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed