BDBM50153705 CHEMBL3774494

SMILES CC(C)CN1CCc2cc(ccc2[C@@]1(C)c3ccc(cc3)/C=C/C(=O)O)O

InChI Key InChIKey=WIYPHWOCUFWQTJ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153705   

TargetEstrogen receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153705(CHEMBL3774494)
Affinity DataIC50: 11nMAssay Description:Downregulation of ERalpha in human MCF7 cells incubated for 18 to 22 hrs by immunofluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed
TargetEstrogen receptor(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50153705(CHEMBL3774494)
Affinity DataIC50: 44nMAssay Description:Displacement of fluormone ES2 from GST-tagged recombinant human ERalpha LBD after 1 hr by Lanthascreen TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/5/2017
Entry Details Article
PubMed