BDBM50153532 3-(2,6-Dichloro-phenyl)-5-propyl-isoxazole-4-carboxylic acid (4-diethylamino-phenyl)-amide::CHEMBL187271

SMILES CCCc1onc(c1C(=O)Nc1ccc(cc1)N(CC)CC)-c1c(Cl)cccc1Cl

InChI Key InChIKey=LEMXNVRNBKBRBC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50153532   

TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153532(3-(2,6-Dichloro-phenyl)-5-propyl-isoxazole-4-carbo...)
Affinity DataIC50: 131nMAssay Description:Ability to displace [125I]ghrelin from cloned human GHS-R expressed in CHO-K cells was determined (Kd of ghrelin is 0.4 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153532(3-(2,6-Dichloro-phenyl)-5-propyl-isoxazole-4-carbo...)
Affinity DataIC50: 492nMAssay Description:Ability to inhibit ghrelin induced increase in intracellular [Ca2+] in CHO-K cells was determined by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed