BDBM50153464 3-(1H-Indol-3-yl)-4-m-tolylamino-pyrrole-2,5-dione::CHEMBL185573

SMILES Cc1cccc(NC2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c1

InChI Key InChIKey=COIXTVPWHVHINJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153464   

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153464(3-(1H-Indol-3-yl)-4-m-tolylamino-pyrrole-2,5-dione...)
Affinity DataIC50: 151nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153464(3-(1H-Indol-3-yl)-4-m-tolylamino-pyrrole-2,5-dione...)
Affinity DataIC50: 151nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153464(3-(1H-Indol-3-yl)-4-m-tolylamino-pyrrole-2,5-dione...)
Affinity DataIC50: 151nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article