BDBM50153461 3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anilino-1H-pyrrole-2,5-dione::3-[1-(3-Imidazol-1-yl-propyl)-1H-indol-3-yl]-4-phenylamino-pyrrole-2,5-dione::CHEMBL366266

SMILES O=C1NC(=O)C(=C1Nc1ccccc1)c1cn(CCCn2ccnc2)c2ccccc12

InChI Key InChIKey=KIWODJBCHRADND-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50153461   

TargetProtein kinase C alpha type(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 331nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 5nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 331nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 21nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibitory concentration against recombinant human Protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/1/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 17nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 3.85E+3nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 770nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PKCbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PKCgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of PKCepsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetProtein kinase C beta type(Human)
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50153461(3-(1-(3-imidazol-1-ylpropyl)-1H-indol-3-yl)-4-anil...)
Affinity DataIC50: 5nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article