BDBM50153381 CHEMBL186482::Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-methoxycarbonylmethyl-benzylcarbamoyl)-thiazolidin-3-yl]-3-oxo-propyl-ammonium;

SMILES COC(=O)Cc1ccc(CNC(=O)[C@@H]2CSCN2C(=O)CC([NH3+])Cc2ccccc2F)cc1

InChI Key InChIKey=FZCVYOKVSXZELZ-UHFFFAOYSA-O

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50153381   

TargetProlyl endopeptidase FAP(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Fibroblast activation protein alpha (seprase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50153381(Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-m...)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human Potassium channel HERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-m...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of Quiescent cell prolyl dipeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-m...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant Dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of prolyl endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetXaa-Pro dipeptidase(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of prolidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase VIIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50153381(Trifluoro-acetate1-(2-fluoro-benzyl)-3-[(R)-4-(4-m...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Dipeptidylpeptidase IXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed