BDBM50153369 CHEMBL3774754

SMILES CC(C(O)=O)c1ccc(c(F)c1)-c1cccc(OC(=O)Nc2ccccc2)c1

InChI Key InChIKey=YTGFYNXDNGRMJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153369   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50153369(CHEMBL3774754)
Affinity DataIC50: 4.12E+4nMAssay Description:Inhibition of FAAH in Sprague-Dawley rat brain homogenates preincubated for 10 mins followed by addition of substrate measured after 30 mins by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50153369(CHEMBL3774754)
Affinity DataIC50: 270nMAssay Description:Inhibition of ovine COX1 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic acid as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Fondazione Istituto Italiano Di Tecnologia

Curated by ChEMBL
LigandPNGBDBM50153369(CHEMBL3774754)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of recombinant human COX2 assessed as production of PGF2-alpha preincubated with compound followed by the addition of 5 uM arachidonic aci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/4/2017
Entry Details Article
PubMed