BDBM50153263 2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-acetamide::CHEMBL184772

SMILES COc1ccc(cc1)N1CCN(CC(=O)Nc2cccc(C)c2)CC1

InChI Key InChIKey=REGCDVFJQDPGCA-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153263   

TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153263(2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity was calculated in calcium flux assay using HEK293 cells co-transfected with human Dopamine receptor D4.4 and Galphaqo5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153263(2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataKi:  88.9nMAssay Description:In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50153263(2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-N-m-tolyl-...)
Affinity DataKi:  101nMAssay Description:In vitro ability to inhibit [3H]spiperone binding to human Dopamine receptor D4.4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed