BDBM50153228 Biphenyl-4-carboxylic acid [4-(2-dimethylamino-ethylcarbamoyl)-3-methoxy-phenyl]-amide::CHEMBL187288

SMILES COc1cc(NC(=O)c2ccc(cc2)-c2ccccc2)ccc1C(=O)NCCN(C)C

InChI Key InChIKey=JWPBTOBINHJMIW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50153228   

TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153228(Biphenyl-4-carboxylic acid [4-(2-dimethylamino-eth...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153228(Biphenyl-4-carboxylic acid [4-(2-dimethylamino-eth...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153228(Biphenyl-4-carboxylic acid [4-(2-dimethylamino-eth...)
Affinity DataIC50: 2.41E+3nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed