BDBM50153199 2-Methoxy-N-(3-morpholin-4-yl-propyl)-4-[3-(3-phenoxy-phenyl)-ureido]-benzamide::CHEMBL187093

SMILES COc1cc(NC(=O)Nc2cccc(Oc3ccccc3)c2)ccc1C(=O)NCCCN1CCOCC1

InChI Key InChIKey=KCKIWWYHRZPHRB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50153199   

TargetMelanin-concentrating hormone receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153199(2-Methoxy-N-(3-morpholin-4-yl-propyl)-4-[3-(3-phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153199(2-Methoxy-N-(3-morpholin-4-yl-propyl)-4-[3-(3-phen...)
Affinity DataIC50: 70nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 2(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153199(2-Methoxy-N-(3-morpholin-4-yl-propyl)-4-[3-(3-phen...)
Affinity DataIC50: 1.00E+5nMAssay Description:Binding affinity against human Melanin-concentrating hormone receptor 2 stably transfected CHO cells was determined using [125I]MCH as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Human)
7Tm Pharma

Curated by ChEMBL
LigandPNGBDBM50153199(2-Methoxy-N-(3-morpholin-4-yl-propyl)-4-[3-(3-phen...)
Affinity DataIC50: 110nMAssay Description:Antagonistic activity against human Melanin-concentrating hormone receptor 1 stably transfected CHO cells was determined using IP3 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed