BDBM50152745 CHEMBL3780730

SMILES [H][C@]12CN(c3ncnc4n(ncc34)-c3ccccc3)[C@]([H])(CN1c1ccccc1OC)C2

InChI Key InChIKey=TWHZOAJMVSHZKC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50152745   

LigandPNGBDBM50152745(CHEMBL3780730)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50152745(CHEMBL3780730)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human GLUT3 expressed in GLUT1 knock-out DLD1 cells assessed as ATP production co-incubated with 300 mM glucose for 16 hrs by CellTiter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed
LigandPNGBDBM50152745(CHEMBL3780730)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GLUT2 expressed in CHO cells assessed as ATP production co-incubated with 30 mM fructose for 16 hrs by CellTiter-Glo assay in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2017
Entry Details Article
PubMed