BDBM50152726 3-((R)-2-Amino-2-phenyl-ethyl)-1-(2,6-difluoro-benzyl)-6-methyl-5-[2-(4-trifluoromethyl-phenyl)-thiazol-4-yl]-1H-pyrimidine-2,4-dione::CHEMBL187243

SMILES Cc1c(-c2csc(n2)-c2ccc(cc2)C(F)(F)F)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1F

InChI Key InChIKey=IWZDQLHUDHMOMN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152726   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152726(3-((R)-2-Amino-2-phenyl-ethyl)-1-(2,6-difluoro-ben...)
Affinity DataKi:  47nMAssay Description:Binding affinity towards cloned human Gonadotropin-releasing hormone receptor expressed in RBL cells was determined by using [125I]GnRH as radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed